THYMIC PEPTIDES IN IMMUNE RECONSTITUTION AND CLINICAL OUTCOME AFTER ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION

Thymic peptides in immune reconstitution and clinical outcome after allogeneic hematopoietic cell transplantation

Abstract: Patients with hematologic malignancies or nonmalignant diseases may undergo allogeneic hematopoietic cell 6.34/6GC transplantation (HCT), which represents a potential curative treatment.However, they are still at risk of life-threatening complications, such as relapse, acute graft-versus-host disease, and opportunistic infections.These co

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A disrupted FOXP3 transcriptional signature underpins systemic regulatory T cell insufficiency in early pregnancy failure

Summary: Regulatory T (Treg) cell defects are implicated in disorders of embryo implantation and placental development, but the origins of Treg cell dysfunction are unknown.Here, we comprehensively JOINT OPTIMIZER analyzed the phenotypes and transcriptional profile of peripheral blood Treg cells in individuals with early pregnancy failure (EPF).Com

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Improvement of annual forage and seed production in the sub-humid zone of Nigeria through supplement irrigation

A two-year study was conducted at Shika in the Northern Guinea Savanna of Nigeria to evaluate several perennial and annual forage species for seasonal and total annual herbage and/or seed production.Over the entire experimental period, total dry matter (DM) yields for grasses, perennial and hay-suited annual legumes varied from 27.5 to 79.1, 18.8 t

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Quantum Measurements from a Logical Point of View

We introduce a logic modelling some aspects of the behaviour of the measurement process, in such a way that no direct mention of quantum states is made, thus avoiding the problems associated to this rather evasive notion.We then study some properties of the models of this logic, and deduce some characteristics that any JOINT OPTIMIZER model (and he

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